Technical & Scientific Reference — Lumnae ONE / PLUS / PRO

Light as a biological signal

A technical reference for physiotherapists, osteopaths, sports coaches and other practitioners evaluating Lumnae panels — wavelength mechanisms, real device settings, and the research literature, with device type (LED vs. laser) always stated plainly.

Photobiomodulation 9 Wavelengths FDA Registered — Class II
Foundation

What is photobiomodulation?

Photobiomodulation (PBM) — also called low-level light therapy — is the application of specific red and near-infrared wavelengths to tissue to influence cellular activity. Unlike thermal lasers, PBM works at non-thermal intensities; effects are photochemical, not heat-driven.

The cellular mechanism

The primary photoreceptor for PBM is cytochrome c oxidase (CCO), Complex IV of the mitochondrial respiratory chain. CCO absorbs photons in the red and near-infrared range — the best-established starting point for PBM's downstream effects.

The photon-to-ATP cascade

Photon absorption by CCO → increased electron transport chain activity → elevated ATP production → downstream cellular signalling → gene expression changes linked to repair and anti-inflammatory activity.

A secondary mechanism is nitric oxide release from CCO, supporting localised vasodilation and microcirculation. A third — most relevant to near-infrared wavelengths — is deeper tissue penetration through an "optical window," where skin, fat and even bone absorb minimally, letting photons reach muscle, joint and connective tissue.

ATP ProductionEnhanced mitochondrial respiration increases cellular energy output — the starting point for every downstream effect described on this page.
🩸Nitric Oxide ReleaseCCO-mediated NO release contributes to localised vasodilation and improved microcirculation in the treated area.
🔬Redox SignallingA transient, low-level rise in reactive oxygen species activates redox-sensitive transcription factors linked to repair.
🌊Tissue PenetrationNIR wavelengths pass through skin, fat and bone with minimal absorption — the "optical window" reaching 3–5cm deep.
Wavelength Science

The 9 wavelengths

Each wavelength interacts with different chromophores at a different tissue depth. Tap a wavelength for depth, target layer, and the research behind it.

Clinical Use

Why practitioners use Lumnae panels

Different specialties reach for different parts of the spectrum. This describes typical use by practice area — not a claim that the device treats any specific diagnosis.

Clinical Application

Body zone targeting guide

Click any zone for recommended wavelengths, protocol, distance and session parameters.

Protocols

7 expert protocols

Actual intensity (%) per wavelength for each preset, as programmed on the device.

Why Sleep excludes NIR

The Sleep preset omits 810/830/850/1060nm. NIR reaches deep tissue and can feel activating; Sleep uses only visible red/amber wavelengths at a longer working distance for a lower-stimulation evening session.

Why Muscle Recovery, Joint Pain and Fat Loss look identical

These three presets share the exact same wavelength/intensity profile (see table below). They're differentiated by recommended working distance and target area, not by wavelength mix — Muscle Recovery and Fat Loss at 15–20cm/10–15cm over larger areas, Joint Pain closer and more localised. Session timer and distance guidance are what change, not the light itself.

Custom mode — 4 personalised slots

Beyond the 7 presets, the panel has 4 fully programmable slots — each wavelength set independently (0–100% intensity, 0–10,000Hz pulse), saved permanently.

See 14 reference configurations in the Custom Protocol Guide →
Advanced Control

Pulse frequency

Pulse cycles light on and off at a set frequency (0–10,000Hz), independently per wavelength.

Continuous wave (0Hz)
No pulsing — maximum total energy per session. Default for most protocols.
Low frequency (1–40Hz)
10Hz is referenced in comfort/recovery PBM literature. 40Hz corresponds to gamma-band neural oscillation, an active neuromodulation research area (see Research section).
Medium frequency (40–1000Hz)
Studied for deeper tissue applications; ~100Hz appears in pre-exercise muscle priming literature.
High frequency (1000–10,000Hz)
Available for advanced customisation. Less established than lower-frequency PBM research.
Dosimetry

Dosage, distance & frequency

PBM follows a biphasic dose-response — the Arndt-Schulz principle. Too little energy under-stimulates; too much can plateau or reduce the effect.

Irradiance (mW/cm²) × Time (s) ÷ 1000 = Dose (J/cm²)

Example: 160 mW/cm² for 600s (10 min) ÷ 1000 = 96 J/cm². The touchscreen shows session time only — calculate J/cm² manually to compare against literature.

Key parameters

Irradiance at 15cm: 160 mW/cm² · Skin: 10–15cm · Deep tissue/joint: 15–25cm · Scalp: 10–20cm · Max per zone/8h: 20 min · Frequency: 3–7×/week

Evidence Base

Selected clinical research

The wavelength panels above link directly to the most relevant single study per wavelength. Below is the fuller reading list — expand for details.

View all cited studies (11)
Safety

Contraindications & precautions

Pregnancy / breastfeedingMedical clearance recommended
Active cancer treatmentOncologist clearance recommended
PhotosensitivityCertain conditions & medications increase sensitivity
Epilepsy / seizuresAvoid pulse mode; goggles mandatory
Open wounds / recent sunburnAvoid direct treatment; wait 2 weeks post-sunburn
HyperthyroidismAvoid prolonged neck/upper chest exposure
Fever / active infectionAvoid sessions until resolved
Eye conditionsGoggles mandatory; ophthalmologist consult for facial use
Implants / medical devicesGenerally safe; verify with physician
Fitzpatrick V–VIStart lower intensity, increase gradually
Clinical disclaimer: Educational and technical reference only — not medical advice. Lumnae panels do not diagnose, treat, cure or prevent any disease. Practitioners should independently evaluate cited evidence. Contact contact@lumnae.com for further information.